Dubnyk's second playoff shutout came almost two years to the day of his first, also against the Blues on April 20, 2015. Martin Hanzal also scored for Minnesota in the second.
Blues goalie Jake Allen made 26 saves. He entered having stopping 114 of the Wild's first 117 shots in the series.
St. Louis still leads the best-of-seven series 3-1 heading into Game 5 at Minnesota on Saturday.