Jordan Howard ran for 147 yards and a pair of touchdowns as the Bears (4-9) dominated a matchup of the NFL's worst offenses. Their rookie quarterback took full advantage of an injury-depleted defense, completing a career-high 25 passes out of 32 attempts for 271 yards. He also ran 4 yards for a score.
The Bengals (5-8) were coming off a 23-20 loss to the Steelers on Monday night that crushed their playoff hopes and gutted their defense.
The Bears piled up a season-high 482 yards against a unit missing starting cornerbacks Adam "Pacman" Jones and Dre Kirkpatrick as well as linebackers Vontaze Burfict and Nick Vigil.
It was Cincinnati's worst home drubbing since a 34-3 loss to Baltimore in 2008. Many of the 52,002 fans headed for the exits early in the fourth quarter.
Everyone in the NFL's lowest-ranked offense had a big game. Tarik Cohen ran for 80 yards, and Kendall Wright caught 10 passes for 107 yards — the first Bears receiver to top 100 yards this season.
Andy Dalton was picked off for the first time since Oct. 22 in Pittsburgh, ending his career-best streak of 193 attempts without an interception. The interception set up Trubisky's 1-yard touchdown pass that put the Bears in control 26-7 early in the fourth quarter, their biggest lead of the season.