Kizzire closed with a 3-under 69 to match Kang at 19-under 269 at Thanksgiving Point. The 29-year-old former Auburn player earned $117,000 to push his tour-leading total to $391,699.
Kang had five back-nine birdies in a 67. He tied for second in the event last year in Sandy.
Kizzire set up his winning putt on the par-4 18th with a wedge shot from 63 yards, after Kang left his 75-yard shot 40 feet short. Kang had birdie chances to win on the final hole of regulation and first playoff hole, but missed 20-foot putts.
Kizzire opened with rounds of 67, 62 and 71 to take a two-stroke lead over Kang into the final round.
Zack Fischer, Garth Mulroy, Tag Ridings, Alex Aragon and Scott Harrington tied for third at 14 under. Harrington shot 66, Mulroy 68, Ridings 69, Aragon 70, and Harrington 71.
Paducah's Rick Cochran III shot a final round 69 and finished tied for 35th at 8-under par.
