Seung Hwan Oh allowed three hits in the ninth but escaped a one-out, bases-loaded jam for his second save.
Leake (2-1) allowed seven hits and only struck out one, but he held the Pirates to a run over 6 1/3 innings. He has won nine of his last 11 decisions against the Pirates dating to Sept. 11, 2012.
The Cardinals have won back-to-back games for the first time this season to improve to 5-9.
Chad Kuhl (1-1) gave up two runs over six innings. He allowed three hits and struck out three.
