The No. 20 Cardinals (9-3) had to replace quarterback Teddy Bridgewater, and that was before a preseason foot injury to star receiver DeVante Parker further complicated matters. Louisville has played three quarterbacks and had to replace seven defensive starters.
And of course, the players have had to adjust to the new coaching staff.
Despite everything, Louisville is heading to the Belk Bowl against No. 13 Georgia (9-3) on Dec. 30 in Charlotte, North Carolina, and can finish its third straight season with double-digit wins — which would be a first for the program.
Petrino said Tuesday that 10 wins is "a milestone that you want to hit every year."